A lot of hangover brands say "clinically studied" without ever showing you the study. Here's a plain-language walkthrough of the actual research behind Easy Tomorrow's core ingredient. The study tested a glutathione-containing yeast extract, not the finished Easy Tomorrow product.*
The study
Song and colleagues published the trial in the journal Nutrients in 2024. The full citation is listed in the references at the end of this article.1
What "randomized, double-blind, placebo-controlled crossover" actually means
Each of those words is doing real work:
- Randomized — participants were randomly assigned to receive either the glutathione-enriched yeast extract or a placebo, reducing the chance that results were skewed by who got what.
- Double-blind — neither the participants nor the researchers running the trial knew who received the real ingredient versus the placebo while the trial was in progress, reducing bias in reporting and measurement.
- Placebo-controlled — there was a comparison group that received an inactive substance, so researchers could isolate the effect of the ingredient itself.
- Crossover — participants received both the ingredient and the placebo at different points in the trial, with each person effectively acting as their own control.
This randomized, double-blind, placebo-controlled crossover design helps reduce several common sources of bias and allows participants to serve as their own controls.
What was measured
The trial measured serum alcohol and acetaldehyde levels and collected self-reported hangover symptom questionnaires, comparing glutathione-enriched yeast extract with placebo.* The chart on our Science page reflects this comparison directly from the published data.
What the study found
The study found significantly lower serum acetaldehyde levels with GSH compared with placebo. Serum alcohol levels were not significantly different between groups. Questionnaire measures of overall hangover symptoms showed no significant difference between GSH and placebo.
What it doesn't claim
It's worth being direct about this: the study measured a physiological marker in a controlled setting, not a guarantee of how any one person will feel after any one night. Easy Tomorrow's products are not intended to diagnose, treat, cure, or prevent any disease, and individual results can vary based on factors like what and how much you drink, your body, and other variables outside the formula itself.*
The bottom line
This is a real, peer-reviewed, methodologically rigorous trial — not a proprietary in-house study or a handful of anecdotes. It's why Easy Tomorrow can put a citation on the page instead of just a claim.*
REFERENCES
1 Song, G., Han, H., Park, S., Sa, S., Chung, W., & Lee, B. Y. (2024). Effects of GSH on Alcohol Metabolism and Hangover Improvement in Humans: A Randomized Double-Blind Placebo-Controlled Crossover Clinical Trial. Nutrients, 16(19), 3262. https://doi.org/10.3390/nu16193262
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
